The Immunologic Function of 1B2+ Double Negative (CD4−CD8−) T Cells in the 2C Transgenic Mouse1
✍ Scribed by Julie A. Margenthaler; M. Wayne Flye
- Book ID
- 116701818
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 267 KB
- Volume
- 126
- Category
- Article
- ISSN
- 0022-4804
No coin nor oath required. For personal study only.
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## Abstract The initial requirement for the emergence of CMV‐specific CD8^+^ T cells is poorly understood. Mice deficient in the cosignaling TNF superfamily member, 4‐1BB, surprisingly developed exaggerated early CD8^+^ T‐cell responses to mouse CMV (MCMV). CD8^+^ T cells directed against acute MCM