✦ LIBER ✦

The immunogenic properties of drug-resistant murine tumor cells do not correlate with expression of the MDR phenotype

✍ Scribed by Jerald J. Killion; Robert Radinsky; Zhongyun Dong; Randi Fishbeck; Patrick Whitworth; Isaiah J. Fidler

Publisher: Springer-Verlag
Year: 1993
Tongue: English
Weight: 817 KB
Volume: 36
Category: Article
ISSN: 0340-7004
DOI: 10.1007/bf01742254

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Spontaneous mutation rates in cloned mur

Spontaneous mutation rates in cloned murine tumors do not correlate with metastatic potential, whereas the prevalence of karyotypic abnormalities in the parental tumors does

✍ Wayne S. Kendal; Rui-Yu Wang; Philip Frost 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 French ⚖ 715 KB

We tested the hypothesis that highly malignant cell lines are genomically more unstable than their less malignant counterparts, and that this instability is more pronounced in clones than in cell lines. We compared MDAY-DZ to its non-metastatic variant, D36W25, with regard to ( I ) the rate of devel

The differential expression of H-2K vers

The differential expression of H-2K versus H-2D antigens, distinguishing high- metastatic from low- metastatic clones, is correlated with the immunogenic properties of the tumor cells

✍ Lea Eisenbach; Nurit Hollander; Lea Greenfeld; Hadas Yakor; Shraga Segal; Michae 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 French ⚖ 700 KB

Two clones of the 3LL Lewis lung carcinoma, a lowmetastatic clone A9 and a high-metastatic clone DIZZ, were studied for MHC expression and immunogenic p r o p erties. Using monoclonal antibodies, we demonstrated that the A9 clone expresses both the H-2Kb and the H-2Db. whereas the D I22 expresses o

Warburg phenotype in renal cell carcinom

Warburg phenotype in renal cell carcinoma: High expression of glucose-transporter 1 (GLUT-1) correlates with low CD8+ T-cell infiltration in the tumor

✍ Katrin Singer; Michael Kastenberger; Eva Gottfried; Christine G. Hammerschmied; 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 904 KB

## Abstract Many tumor cells are characterized by a dysregulated glucose metabolism associated with increased glycolysis in the presence of oxygen (“Warburg Effect”). Here, we analyzed for the first time a possible link between glucose metabolism and immune cell infiltration in renal cell carcinoma

Expression of the bcl-2 gene family in n

Expression of the bcl-2 gene family in normal and malignant breast tissue: Low bax-α expression in tumor cells correlates with resistance towards apoptosis

✍ Railf C. Bargou; Peter T. Daniel; Markus Y. Mapara; Kurt Bommert; Christian Wage 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 799 KB

We have studied the expression of the apoptosis-regulating genes bcl-2, bcl-x, box and APO-I /fas (CD95) in human breast cancer. The expression pattern of these genes in human breast-cancer tissues and breast-cancer-derived cell lines was compared to that seen in normal breast epithelium and breast

The loss of class II MHC antigen express

The loss of class II MHC antigen expression byras-transformed murine fibroblasts passaged as tumours correlates with increased tumorigenicity but is not mediated by T cells

✍ Alan G. Morris; Richard L. Darley; Wendy J. Bateman 📂 Article 📅 1992 🏛 Springer-Verlag 🌐 English ⚖ 661 KB

Co-ordinated over-expression of the MRP

Co-ordinated over-expression of the MRP and γ-glutamylcysteine synthetase genes, but not MRD1, correlates with doxorubicin resistance in human malignant mesothelioma cell lines

✍ Besim Ogretmen; Hamid R. Bahadori; Mary D. McCauley; Alice Boylan; Mark R. Green 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 84 KB 👁 1 views

While human malignant mesothelioma is extremely resistant to chemotherapy, its intrinsic resistance mechanisms remain largely unknown. In this study, we used normal human mesothelial cells and 5 human mesothelioma cell lines not previously exposed to chemotherapeutic agents to demonstrate that the m