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The Immune Response Modifier Resiquimod Mimics CD40-Induced B Cell Activation

✍ Scribed by Gail A. Bishop; Luis M. Ramirez; Mekhine Baccam; Lisa K. Busch; Linda K. Pederson; Mark A. Tomai


Book ID
112240391
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
134 KB
Volume
208
Category
Article
ISSN
0008-8749

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This study tracks the fate of antigen-reactive B cells through follicular and extrafollicular responses and addresses the function of CD40 in these processes. The unique feature of this system is the use of transgenic B cells in which the heavy chain locus has been altered by site-directed insertion