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Dendritic Cell Maturation and Subsequent Enhanced T-Cell Stimulation Induced with the Novel Synthetic Immune Response Modifier R-848

✍ Scribed by Cory L. Ahonen; Sheila J. Gibson; Rose M. Smith; Linda K. Pederson; Jana M. Lindh; Mark A. Tomai; John P. Vasilakos

Book ID
112240179
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
208 KB
Volume
197
Category
Article
ISSN
0008-8749

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## Abstract ## Background Tumor antigen presentation by dendritic cells (DCs) to T cells in lymphoid organs is crucial for induction of antitumor immune responses. Fms‐like tyrosine kinase 3 ligand (Flt3L) is a regulator of hematopoietic cell development. ## Methods To investigate the potential