𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The identification of particulate matter in biological tissues and fluids

✍ Scribed by P. R. Crocker; P. A. Dieppe; Gina Tyler; S. K. Chapman; D. A. Willoughby

Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
474 KB
Volume
121
Category
Article
ISSN
0022-3417

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✦ Synopsis

Sections, 1-2 micron thick, of Araldite embedded tissue were prepared to provide a link between optical and electron microscopy for the identification of crystals. This technique permits examination of individual particles by means of polarising light microscopy, electron microscopy, X-ray energy spectroscopy and electron diffraction. It provides a reliable method for routine and research studies. It has led to the positive identification of individual crystals of calcium pyrophosphate dihydrate and hydroxyapatite in synovial fluids. The method can be applied to the identification of other particulate matter in a variety of biological specimens.

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