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The hypotensive effects of chlorothiazide and hydrochlorothiazide: A critical comparison

✍ Scribed by J.Marion Bryant; Natalio Schvartz; Maria Roque; Lucian Fletcher; Harrison Fertig; David P. Lauler


Book ID
115661646
Publisher
Elsevier Science
Year
1961
Tongue
English
Weight
415 KB
Volume
7
Category
Article
ISSN
0002-9149

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The binding of hydrochlorothiazide and chlorothiazide to milk has been measured. Experiments were carried out at 5, 15, 25, and 37 degrees C on bovine milk samples with fat contents of 0.75, 1.70, and 3.50%, using a wide range of drug concentrations to mimic concentrations encountered when a drug-mi