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The hypervariable region of the HCV genome changes sequentially during the progression of acute HCV infection to chronic hepatitis

✍ Scribed by Nobuyuki Enomoto; Naoya Sakamoto; Masayuki Kurosaki; Fumiaki Marumo; Chifumi Sato


Book ID
118566207
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
162 KB
Volume
17
Category
Article
ISSN
0168-8278

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πŸ“œ SIMILAR VOLUMES


Sequential change of the hypervariable r
✍ Naoya Sakamoto; Nobuyuki Enomoto; Masayuki Kurosaki; Fumiaki Marumo; Chifumi Sat πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 512 KB

## Abstract Hepatitis C virus (HCV) infection is characterized by persistence of liver inflammation that often leads to end‐stage liver disease, although the mechanisms are not fully understood. A hyper‐variable region (HVR) has been reported in the E2/NS1 region of the HCV genome, in which strikin

Rapid sequence variation of the hypervar
✍ Masayuki Kurosaki; Nobuyuki Enomoto; Fumiaki Marumo; Chifumi Sato πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 798 KB

To evaluate the clinical significance of sequence variations in the hypervariable region of hepatitis C virus during the course of chronic infection, we performed pairwise comparison of the predominant nucleotide sequences. Hepatitis C virus RNA was extracted from two plasma samples obtained from 12