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The Hydrolysis of Amino Groups in Certain 2,4,5,6-Tetrasubstituted Pyrimidines

โœ Scribed by Taylor, E. C.; Cain, C. K.


Book ID
126306378
Publisher
American Chemical Society
Year
1949
Tongue
English
Weight
297 KB
Volume
71
Category
Article
ISSN
0002-7863

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## Abstract magnified image The synthesis of 2โ€aminoโ€4โ€hydroxylโ€6โ€hydroxymethylโ€5,6,7,8โ€tetrahydropyrido[3,2โ€d]pyrimidine **3** is described from 2โ€aminoโ€6โ€methyluracil **4** through the crucial step of 2โ€pivaloyl protecting and cyclization. The assignment of the structure of **3** was performed by