Band 1q12 is a breakage prone region commonly involved in chromosome 1 rearrangements found in human cancer. We have investigated whether a lack of DNA repair can account for the observed 1q12 fragility. Ethyl methanesulfonate (EMS)-induced repair sites originating in G0/G1 phase of the cell cycle w
The human Y chromosome shows a low level of DNA polymorphism
β Scribed by P. MALASPINA; F. PERSICHETTI; A. NOVELLETTO; C. IODICE; L. TERRENATO; J. WOLFE; M. FERRARO; G. PRANTERA
- Book ID
- 115249436
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 685 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0003-4800
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A systematic search for restriction fragment length polymorphisms (RFLPs) on the human Y chromosome was performed. DNA samples from 16-34 individuals were screened with five restriction enzymes and 12 Y-chromosomal probes, 3 of which detect lowly repetitive sequences and 9 of which are apparently si