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The Human Preprotachykinin-A Gene Promoter Has Been Highly Conserved and Can Drive Human-like Marker Gene Expression in the Adult Mouse CNS

โœ Scribed by Alasdair MacKenzie; Catherine Payne; Shelagh Boyle; Alan R. Clarke; John P. Quinn

Book ID
115637688
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
589 KB
Volume
16
Category
Article
ISSN
1044-7431

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## Abstract The tyrosinase promoter has been used to target expression of the mutated human T24 Haโ€__ras__ oncogene in pigmentโ€producing cells of transgenic mice. Two independent founder mice carrying the transgene survived and showed the same distinct phenotype of muted coat color, deeply pigmente