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The human PDGF receptor α-subunit gene maps to chromosome 4 in close proximity to c-kit

✍ Scribed by R. G. K. Gronwald; D. A. Adler; J. D. Kelly; C. M. Disteche; D. F. Bowen-Pope


Publisher
Springer
Year
1990
Tongue
English
Weight
301 KB
Volume
85
Category
Article
ISSN
0340-6717

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✦ Synopsis


The gene encoding the alpha-subunit of the human platelet-derived growth factor receptor (PDGFRA) maps to band q11-q12 of chromosome 4 by in situ hybridization, which was confirmed by Southern analysis of a Chinese hamster x human cell hybrid that retains only human chromosome 4.


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Human PDGFA receptor gene maps to the sa
✍ Dr. Göran Stenman; Anders Eriksson; Lena Claesson-Welsh 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 379 KB

The gene for the human platelet-derived growth factor (PDGF) A type receptor was assigned to the proximal long arm of chromosome 4 by using in situ hybridization. Of 14 I labeled metaphase cells, 74 had grains over chromosome 4, with a distinct peak at bands q l I-ql2. The presence of the gene on ch