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The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons

โœ Scribed by Csaba Finta; Peter G. Zaphiropoulos


Book ID
117520120
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
359 KB
Volume
260
Category
Article
ISSN
0378-1119

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Cytochrome P450 genes from the CYP2A, CYP2B, and C Y P 2 F subfamilies form a tight cluster which we have localized on the detailed physical map of human chromosome 19. The corresponding three gene subfamilies are also clustered in the mouse genome, on the region of chromosome 7 known to be syntenic