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The human aminopeptidase N gene: isolation, chromosome localization, and DNA polymorphism analysis

โœ Scribed by Valerie M. Watt; Huntington F. Willard

Publisher
Springer
Year
1990
Tongue
English
Weight
522 KB
Volume
85
Category
Article
ISSN
0340-6717

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โœฆ Synopsis

DNA encoding the human aminopeptidase N (EC 3.4.11.2) gene (PEPN) was first isolated using rat cDNA probes and then used in Southern analysis of DNA from mouse-human somatic cell hybrids to assign this gene to the long-arm region (q11-qter) of human chromosome 15. This human genomic DNA probe detects a frequent DraIII polymorphism that is a useful marker for human chromosome 15.

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