The human adenylate kinase 9 is a nucleoside mono- and diphosphate kinase
β Scribed by Amiri, Marjan; Conserva, Francesca; Panayiotou, Christakis; Karlsson, Anna; Solaroli, Nicola
- Book ID
- 120240137
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 912 KB
- Volume
- 45
- Category
- Article
- ISSN
- 1357-2725
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Human NDP kinase B, product of the nm23-H2 gene, binds DNA. It has been suggested that a helix hairpin on the protein surface, part of the nucleotide substrate binding site, could accommodate DNA binding by swinging away. The presence of flexible regions was therefore investigated by 1 H NMR dynamic
## Abstract Strong evidence is given that a nucleoside diphosphate kinase is present to some extent on the surface of intact neoplastic cells in culture. Experiments could be performed with cells cultured in a few plates to which an incubation medium was added. The cells were firmly attached to the