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The HMG-CoA Reductase Inhibitor Fluvastatin Inhibits Insect Juvenile Hormone Biosynthesis

✍ Scribed by Stéphane Debernard; Françoise Rossignol; Franck Couillaud

Book ID
112245761
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
298 KB
Volume
95
Category
Article
ISSN
0016-6480

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The absorption and disposition of fluvastatin have been studied in the female rabbit. In naive rabbits receiving a single oral dose (1 mg kg-I) of [3H]fluvastatin, absorption was rapid and amounted to c. 90 per cent compared with an intravenous reference dose. The drug was subject to considerable fi