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Vascular endothelial cell apoptosis by the HMG-CoA reductase inhibitor fluvastatin: a response blocked by glucocorticoids


Book ID
105723335
Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
464 KB
Volume
170
Category
Article
ISSN
1863-4362

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Although the efficacy of fluvastatin (HMG-CoA reductase inhibitor) in the treatment of primary hypercholesterolemia is well documented, a wide interindividual variation treatment response has been observed. We have studied the possible role of the AvaII (exon 13), HincII (exon 12), and PvuII (intron