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The High-Level Expression of Human Tissue Plasminogen Activator in the Milk of Transgenic Mice with Hybrid Gene Locus Strategy

โœ Scribed by Yanrong Zhou; Yanli Lin; Xiaojie Wu; Fuyin Xiong; Yuemeng Lv; Tao Zheng; Peitang Huang; Hongxing Chen


Book ID
107581940
Publisher
Humana Press Inc
Year
2011
Tongue
English
Weight
356 KB
Volume
50
Category
Article
ISSN
1073-6085

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The human tissue plasminogen activator (h-tPA) cDNA was fused either with the leader sequence of the killer toxin of Kluyveromyces lactis or with the Saccharomyces diastaticus glucoamylase leader peptide and cloned in the yeast expression vector under the control of the inducible USAgal/CYC1 promote