✦ LIBER ✦

High level expression of human tissue kallikrein in the circulation induces hypotension in transgenic mice

✍ Scribed by Qing Song; Julie Chao; Lee Chao

Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 181 KB
Volume: 32
Category: Article
ISSN: 0162-3109
DOI: 10.1016/0162-3109(95)00065-8

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Liver-specific and high-level expression

Liver-specific and high-level expression of human serum amyloid P component gene in transgenic mice

✍ Iwanaga, Tomohisa ;Wakasugi, Shoji ;Inomoto, Takeaki ;Uehira, Masahiro ;Ohnishi, 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 644 KB

To analyze the regulation of human serum amyloid P component (SAP) gene expression, we have produced seven transgenic mice. The 3.3 kb human SAP genes containing about 0.8 kb of 5' and 1.5 kb of 3' flanking region were injected into fertilized eggs of C57BL/6 mice. In five of the seven transgenic mi

K:CI cotransport in red cells of transge

K:CI cotransport in red cells of transgenic mice expressing high levels of human hemoglobin S

✍ Romero, José R.; Fabry, Mary E.; Suzuka, Sandra M.; Costantini, Frank; Nagel, Ro 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 60 KB

Cl cotransport is involved in generating dense red blood cells (RBCs) in homozygotes for HbS (SS). We report on the properties of this transport system in RBCs from control and transgenic mice expressing high levels of human ␣ H and ␤ S chains. Unlike human SS RBCs, mouse RBCs incubated in isotonic

Mice expressing high levels of soluble C

Mice expressing high levels of soluble CD14 retain LPS in the circulation and are resistant to LPS-induced lethality

✍ Berri Jacque; Kristin Stephan; Irina Smirnova; Bobae Kim; Damian Gilling; Alexan 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 250 KB

Local expression of human growth hormone

Local expression of human growth hormone in bone results in impaired mechanical integrity in the skeletal tissue of transgenic mice

✍ Kuo-Fung Tseng; Jeffrey F. Bonadio; Timothy A. Stewart; Andrew R. Baker; Steven 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 776 KB

## Abstract The effect of local production of human growth hormone on murine cortical bone was investigated using a transgenic mouse model. Femora and humeri from human growth hormone transgenic mice and littermate control mice were obtained, and the geometrical, biomechanical, compositional, and h

Transgene expression of human PON1 Q in

Transgene expression of human PON1 Q in mice protected the liver against CCl4-induced injury

✍ Chi Zhang; Wei Peng; Xiaoling Jiang; Bo Chen; Jie Zhu; Yuhui Zang; Junfeng Zhang 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 277 KB

## Background: Oxidative stress, often in association with decreased antioxidant defenses, plays a pathogenetic role in both initiation and progression of liver injuries, leading to almost all clinical and experimental conditions of chronic liver diseases. human paraoxonase 1 (hpon1) is a liver-syn

Transgenic expression of cholesterol 7α-

Transgenic expression of cholesterol 7α-hydroxylase in the liver prevents high-fat diet–induced obesity and insulin resistance in mice

✍ Tiangang Li; Erika Owsley; Michelle Matozel; Peter Hsu; Colleen M. Novak; John Y 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 837 KB

Cholesterol 7a-hydroxylase (CYP7A1) is the rate-limiting enzyme in the bile acid biosynthetic pathway that converts cholesterol into bile acids in the liver. Recent studies have shown that bile acids may play an important role in maintaining lipid, glucose, and energy homeostasis. However, the role