๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

The HGAR1 familial hypercholesterolemia pedigree

โœ Scribed by Dr. Joan E. Bailey-Wilson; Robert C. Elston


Book ID
102226126
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
144 KB
Volume
10
Category
Article
ISSN
0741-0395

No coin nor oath required. For personal study only.

โœฆ Synopsis


Data on 232 members of a single pedigree, descended from two pairs of original parents, were made available to the participants of Genetic Analysis Workshop 8 (GAWS). In addition to information concerning age and sex, measurements for 10 quantitative traits and genotypes at 22 polymorphic marker loci were also provided for a subset of 193 of these family members. 1993 Wiley-Liss, Inc.


๐Ÿ“œ SIMILAR VOLUMES


Genetic diagnosis of familial hyperchole
โœ Stanley H. Hsia; Philip W. Connelly; Robert A. Hegele ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 774 KB

Objectives: To describe a process of diagnosing familial hypercholesterolemia (FH) at the DNA level in selected family members of affected individuals. ## Design and Methods: A 63-year-old male patient presented with cholesterol elevations consistent with heterozygous familial hypercholesterolemi

Linkage analysis in a large pedigree asc
โœ Dr. Joan E. Bailey-Wilson; Alexander F. Wilson; Vaneeta Bamba ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 313 KB

Sib-pair linkage analysis was used to screen a large pedigree, ascertained through four members with hypercholesterolemia, for evidence of linkage between 12 quantitative traits and 15 genetic marker loci. Traits were analyzed on the untransformed, natural log and square root-transformed scales. Aft

Segregation analysis of plasma lipoprote
โœ Yechiel Friedlander; Eran Leitersdorf ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 999 KB

The role of genetic and environmental factors in determining the variability in plasma lipoprotein(a) [Lp(a)] levels was investigated in 220 members of 14 families with familial hypercholesterolemia (FH) whose plasma Lp(a) levels were previously reported [Leitersdorf et al. (1 99 1) J Lipid Res 32: