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The Hepatitis C Virus Internal Ribosome Entry Site Adopts an Ion-dependent Tertiary Fold

✍ Scribed by Jeffrey S. Kieft; Kaihong Zhou; Ronald Jubin; Michael G. Murray; Johnson Y.N. Lau; Jennifer A. Doudna

Book ID: 115629625
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 675 KB
Volume: 292
Category: Article
ISSN: 0022-2836
DOI: 10.1006/jmbi.1999.3095

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## Abstract The extreme 5′‐proximal sequence of the hepatitis C virus (HCV) genome including the 5′ non‐coding region (5′NCR) of 341 nucleotide long and the first 30 nucleotides of the core region is highly conserved among different HCV genotypes. It contains a segment termed Internal Ribosome Entr