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The hepatitis B virus X protein abrogates Bcl-2-mediated protection against Fas apoptosis in the liver

✍ Scribed by Terradillos, Olivier; de La Coste, Alix; Pollicino, Teresa; Neuveut, Christine; Sitterlin, Delphine; Lecoeur, Hervé; Gougeon, Marie-Lise; Kahn, Axel; Buendia, Marie-Annick


Book ID
110066331
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
375 KB
Volume
21
Category
Article
ISSN
0950-9232

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## Abstract We have recently reported that the naturally occurring spliced variant of Hepatitis B virus protein, HBSP, displayed proapoptotic activity through its BH3 domain. To investigate whether the BH3 domain in HBSP interacted with Bcl‐2 family of proteins, HBSP and Bcl‐2 family of proteins we