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The Hedgehog and Wnt signalling pathways in cancer

✍ Scribed by Taipale, Jussi; Beachy, Philip A.

Book ID: 109774697
Publisher: Nature Publishing Group
Year: 2001
Tongue: English
Weight: 387 KB
Volume: 411
Category: Article
ISSN: 0028-0836
DOI: 10.1038/35077219

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## Abstract Pancreatic cancer is an aggressive malignancy that exhibits a number of genetic and epigenetic alterations. Indian hedgehog (Ihh) and its 2 signaling receptors, patched (Ptc) and smoothened (Smo), are involved in pancreatic development and regulation of β‐cell function as well as in cer