The haplotype of the MxA gene promoter is associated with hepatitis B virus infection in a Chinese population
โ Scribed by Bangwei Cao; Xing Liu; Fang Hou; Wende Li; Zhonggang Han; Qipeng Zhang; Yue Dai; Changqing Xu; Huimin Qi
- Book ID
- 111239118
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 172 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0106-9543
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Interferon-c (IFN-c) is a pleiotropic cytokine that plays an important role in regulating cellular immune responses. Regulation of IFN-c expression is considered to be strictly controlled at the transcriptional level. Two single-nucleotide polymorphisms (SNPs) within the human IFN-c promoter (at pos
## Abstract A number of genetic loci have been proposed to be associated with persistent hepatitis B virus (HBV) infection. This study aimed to evaluate the association and interaction of susceptible genes with HBV persistence in a Chinese population. A total of 17 polymorphisms in 9 candidate gene