Interferon-c (IFN-c) is a pleiotropic cytokine that plays an important role in regulating cellular immune responses. Regulation of IFN-c expression is considered to be strictly controlled at the transcriptional level. Two single-nucleotide polymorphisms (SNPs) within the human IFN-c promoter (at pos
Association of interferon-gamma gene haplotype in the Chinese population with hepatitis B virus infection
โ Scribed by Meiqiang Liu; Bangwei Cao; Hongkun Zhang; Yue Dai; Xiaolin Liu; Changqing Xu
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 130 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0093-7711
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## Abstract Nineteen Chinese patients with chronic hepatitis B virus (HBV) infection, seropositive for HBV e antigen (HBeAg) and HBV DNA on at least three occasions in 6 months, were randomised to receive either recombinant human interferongamma (rlFNฮณ) 0.1 mg/m^2^ intramuscularly thrice weekly for