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The Hansenula polymorpha PDD7 gene is essential for macropexophagy and microautophagy

✍ Scribed by Janet A Komduur; Marten Veenhuis; Jan A.K.W Kiel

Book ID
117797689
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
815 KB
Volume
3
Category
Article
ISSN
1567-1356

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TheHansenula polymorpha PDD1 gene produc
TheHansenula polymorpha PDD1 gene product, essential for the selective degradation of peroxisomes, is a homologue ofSaccharomyces cerevisiae Vps34p
✍ Kiel, J. A. K. W.; Rechinger, K. B.; van der Klei, I. J.; Salomons, F. A.; Titor πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 502 KB

Via functional complementation we have isolated the Hansenula polymorpha PDD1 gene essential for selective, macroautophagic peroxisome degradation. HpPDD1 encodes a 116 kDa protein with high similarity (42% identity) to Saccharomyces cerevisiae Vps34p, which has been implicated in vacuolar protein s