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The GST deletions and NQO1*2 polymorphism confers interindividual variability of response to treatment in patients with acute myeloid leukemia

โœ Scribed by Eva Barragan; Maria Collado; Jose Cervera; Guillermo Martin; Pascual Bolufer; Jose Roman; Miguel A. Sanz

Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
469 KB
Volume
31
Category
Article
ISSN
0145-2126

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Glutathione S-transferases (GSTT1 and GS
Glutathione S-transferases (GSTT1 and GSTM1) genes polymorphisms and the treatment response and prognosis in Chinese patients with de novo acute myeloid leukemia
โœ Zhijian Xiao; Lin Yang; Zefeng Xu; Yue Zhang; Liang Liu; Ling Nie; Lin Li; Jianx ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 224 KB

We investigated the prognostic significance of genetic polymorphism for glutathione S-transferase theta 1 (GSTT1) and glutathione S-transferase mu 1 (GSTM1) in 254 Chinese patients with de novo acute myeloid leukemia (AML) other than AML-M3. The early death rate after the initiation of chemotherapy