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The growing impact of click chemistry on drug discovery

✍ Scribed by Hartmuth C Kolb; K.Barry Sharpless


Book ID
114384580
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
145 KB
Volume
8
Category
Article
ISSN
1359-6446

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Click chemistry, the subject of this tutorial review, is a modular synthetic approach towards the assembly of new molecular entities. This powerful strategy relies mainly upon the construction of carbon-heteroatom bonds using spring-loaded reactants. Its growing number of applications are found in n