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The Gould—Jacob Type of Reaction for the Synthesis of Novel Pyrimidopyrrolopyrimidines: A Comparison of Classical Heating vs. Solvent-Free Microwave Irradiation.

✍ Scribed by Nirmal D. Desai


Publisher
John Wiley and Sons
Year
2007
Weight
24 KB
Volume
38
Category
Article
ISSN
0931-7597

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Abstract

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The gould-jacob type of reaction for the
✍ Nirmal D. Desai 📂 Article 📅 2006 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 295 KB

The Gould-Jacob type of reaction for the synthesis of ethyl 4-oxo-8,10-substituted-4,8-dihydropyrimido[1,2c]pyrrolo [3,2-e]pyrimidine-3-carboxylates 5 has been carried out conventionally by the condensation between 4aminopyrrolo[2,3-d]pyrimidines 2 and diethyl ethoxymethylenemalonate 3 via acyclic i