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The glycine site of NMDA receptors—A target for treatment of schizophrenia

✍ Scribed by Joachim F. Hallmayer


Book ID
107551811
Publisher
Springer
Year
2006
Tongue
English
Weight
71 KB
Volume
8
Category
Article
ISSN
1523-3812

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Hypofunction of the N-methyl-D-aspartate receptor (NMDAR) has been implicated in the pathophysiology of schizophrenia. The NMDAR contains a D-serine/glycine site on the NR1 subunit that may be a promising therapeutic target for psychiatric illness. This review outlines the complex regulation of endo