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The Glycal Assembly Method on Solid Supports: Synthesis of Oligosaccharides and Glycoconjugates

✍ Scribed by Pier F. Cirillo; Samuel J. Danishefsky


Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
33
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A Paradigm Case for
✍ K. K.-C. LIU; S. J. DANISHEFSKY πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 28 KB πŸ‘ 1 views

A Paradigm Case for the Merging of Glycal and Enzymatic Assembly Methods in Glycoconjugate Synthesis: A Highly Efficient Chemo-Enzymatic Synthesis of GM3 (I). -A concise, regio-and stereoselective synthesis of the ganglioside (I) is achieved by enzymatically mediated introduction of the sialic acid