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ChemInform Abstract: A Paradigm Case for the Merging of Glycal and Enzymatic Assembly Methods in Glycoconjugate Synthesis: A Highly Efficient Chemo- Enzymatic Synthesis of GM3 (I).

✍ Scribed by K. K.-C. LIU; S. J. DANISHEFSKY


Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


A Paradigm Case for the Merging of Glycal and Enzymatic Assembly Methods in Glycoconjugate Synthesis: A Highly Efficient Chemo-Enzymatic Synthesis of GM3 (I).

-A concise, regio-and stereoselective synthesis of the ganglioside (I) is achieved by enzymatically mediated introduction of the sialic acid residue at C-3 of the lactose. -(LIU, K. K.-C.;