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The Giant Elastic Protein Titin Role in Muscle Function and Disease

โœ Scribed by Granzier, Henk


Book ID
122298321
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
40 KB
Volume
98
Category
Article
ISSN
0006-3495

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The evolution of titin and related giant
โœ Desmond G. Higgins; Siegfried Labeit; Mathias Gautel; Toby J. Gibson ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Springer ๐ŸŒ English โš– 914 KB

Titin and twitchin are giant proteins expressed in muscle. They are mainly composed of domains belonging to the fibronectin class III and immunoglobulin c2 families, repeated many times. In addition, both proteins have a protein kinase domain near the C-terminus. This paper explores the evolution of