The genomic complexity of primary human prostate cancer
โ Scribed by Berger, Michael F.; Lawrence, Michael S.; Demichelis, Francesca; Drier, Yotam; Cibulskis, Kristian; Sivachenko, Andrey Y.; Sboner, Andrea; Esgueva, Raquel; Pflueger, Dorothee; Sougnez, Carrie
- Book ID
- 109900369
- Publisher
- Nature Publishing Group
- Year
- 2011
- Tongue
- English
- Weight
- 873 KB
- Volume
- 470
- Category
- Article
- ISSN
- 0028-0836
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## Abstract Lack of hormone dependency in prostate cancers is an irreversible event that occurs through generation of genomic instability induced by androgen deprivation. Indeed, the cytogenetic profile of hormoneโdependent (HD) prostate cancer remains stable as long as it received a hormone supply