The Genome-Wide Association Study—A New Era for Common Polygenic Disorders
✍ Scribed by Robert Roberts; George A. Wells; Alexandre F. R. Stewart; Sonny Dandona; Li Chen
- Book ID
- 107639505
- Publisher
- Springer US
- Year
- 2010
- Tongue
- English
- Weight
- 197 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1937-5387
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Bone mineral density (BMD) is a heritable trait, and in mice, over 100 quantitative trait loci (QTLs) have been reported, but candidate genes have been identified for only a small percentage. Persistent errors in the mouse genetic map have negatively affected QTL localization, spurring the developme
## Abstract The large number of markers considered in a genome‐wide association study (GWAS) has resulted in a simplification of analyses conducted. Most studies are analyzed one marker at a time using simple tests like the trend test. Methods that account for the special features of genetic associ