The impact of genetic factors on the pathogenesis of allergy and asthma is currently an area of intense investigation. Although epidemiological studies find more and more genes that are likely to contribute to allergic inflammation, functional studies of the mechanisms that link genetic variation wi
The genetics and complexity of allergy and asthma
โ Scribed by Kathleen C Barnes; David G Marsh
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 203 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0167-5699
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## Abstract No Abtract
Genome-wide screens are consistently finding linkage between asthma-associated traits and specific chromosomal loci. Several loci coincide with linkages to other inflammatory diseases, suggesting the presence of common pathways in their pathogenesis. Candidate-gene studies have found an association
## Aims To examine the prevalence of symptoms of asthma and allergy in different farming groups in New Zealand. Methods A postal questionnaire was sent to a random sample of 2,500 farmers throughout New Zealand. Results The response rate was 77% (1,706 of 2,203 eligibles). The 12-month period prev