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The genetic polymorphism of sparteine metabolism

โœ Scribed by Eichelbaum, M.; Reetz, K.-P.; Schmidt, E. K.; Zekorn, C.


Book ID
125836598
Publisher
Informa plc
Year
1986
Tongue
English
Weight
411 KB
Volume
16
Category
Article
ISSN
0049-8254

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Genetically determined sparteine oxidati
โœ K. Orzechowska-Juzwenko; J. Pawlik; P. Niewiล„ski; P. Milejski; J. Dembowski; J. ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Springer ๐ŸŒ English โš– 259 KB

The genetic oxidation polymorphism was determined in 160 healthy Polish volunteers from the southwest of Poland (Wroctaw region), using sparteine as a model drug. The results of a Polish population study revealed a bimodal distribution of the sparteine metabolic ratio and showed the existence of two