Genetics of human cancer
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Alfred G. Knudson Jr.
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Article
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1986
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John Wiley and Sons
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English
โ 559 KB
To the extent that cancer can be caused by somatic mutations) any understanding of carcinogenesis depends upon knowledge of the genes that are mutated. Two large classes of such genes have been discovered: (1) oncogenes, whose existence was revealed by the study of the animal retroviruses, and (2) a