𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Genetics of human cancer

✍ Scribed by Alfred G. Knudson Jr.

Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
559 KB
Volume
129
Category
Article
ISSN
0021-9541

No coin nor oath required. For personal study only.

✦ Synopsis

To the extent that cancer can be caused by somatic mutations) any understanding of carcinogenesis depends upon knowledge of the genes that are mutated. Two large classes of such genes have been discovered: (1) oncogenes, whose existence was revealed by the study of the animal retroviruses, and (2) antioncogenes, which were revealed by the study of hereditary cancer in man. It is this second class of genes that I will discuss at this symposium.

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