𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The genes for human gastrin and cholecystokinin are located on different chromosomes

✍ Scribed by T. Lund; A. H. M. Geurts van Kessel; S. Haun; J. E. Dixon

Publisher
Springer
Year
1986
Tongue
English
Weight
484 KB
Volume
73
Category
Article
ISSN
0340-6717

No coin nor oath required. For personal study only.

✦ Synopsis

The polypeptide hormones gastrin and cholecystokinin are structurally related, having the identical pentapeptide GWMDF located at their C-terminus. The precursors to these two hormones also show amino acid homology, suggesting that they may have a common ancestral origin. Recombinant DNA clones corresponding to gene fragments encoding human gastrin and cholecystokinin were used to determine their respective chromosomal localization by analyzing human-rodent cell lines. We have assigned the cholecystokinin gene to human chromosome 3q12-3pter and the gastrin gene to chromosome 17q.

πŸ“œ SIMILAR VOLUMES

The genes forCD37, CD53, andR2, all memb
The genes forCD37, CD53, andR2, all members of a novel gene family, are located on different chromosomes
✍ Kimmo I. Virtaneva; Pavla AngelisovΓ‘; Thomas Baumruker; VΓ‘clav HoΕ™ejΕ‘Γ­; Heli Nev πŸ“‚ Article πŸ“… 1993 πŸ› Springer-Verlag 🌐 English βš– 524 KB

CD37, CD53, and R2 leukocyte surface antigens are members of a novel family of structurally related proteins. They all have four transmembrane-spanning domains with a single major extracellular loop. The CD37 is expressed on B cells and on a subpopulation of T cells. The CD53 is known as a panleukoc