Effect of molecular size on carbonic anh
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Kamal Kumar; Mahesh C. Bindal; Prithvi Singh; Satya P. Gupta
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Article
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1981
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John Wiley and Sons
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English
β 310 KB
## Abstract The molecular size is found to play an important role in carbonic anhydrase (CA) inhibition by sulfonamides. Significant correlation is obtained between the inhibitory power of __meta__βsubstituted analogs and the van der Waals volume (__V__~__w__~) of the substitutents. This provides a