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The gene for human fibroblast interferon (IFB) maps to 9p21

✍ Scribed by L. Henry; J. Sizun; C. Turleau; J. Boue; M. Azoulay; C. Junien


Book ID
104708763
Publisher
Springer
Year
1984
Tongue
English
Weight
277 KB
Volume
68
Category
Article
ISSN
0340-6717

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Trisomy 21 human fibroblasts are more sensitive to human interferon-alpha (IFN-alpha) than are diploid controls, consistent with the location of the gene (IFRC) which codes for the IFN-alpha receptor on chromosome 21. When compared in the antiviral assay, the difference in sensitivity is five- to te