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The Gene Coding for Glial Cell Line Derived Neurotrophic Factor (GDNF) Maps to Chromosome 5p12-p13.1

✍ Scribed by D. Schindelhauer; S. Schuffenhauer; T. Gasser; A. Steinkasserer; T. Meitinger

Book ID
115612764
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
202 KB
Volume
28
Category
Article
ISSN
0888-7543

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Neurotrophic factors are essential neurone survival promoting molecules that are often secreted and that bind to neuronal cell surface receptors. Glial cell line-derived neurotrophic factor, GDNF, is a potent neurotrophic factor that promotes the survival of dopaminergic neurones in cultures includi