𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The G972R variant of the Insulin Receptor Substrate-1 (IRS-1) gene, body fat distribution and insulin-resistance

✍ Scribed by M. G. Baroni; M. Arca; F. Sentinelli; R. Buzzetti; F. Capici; S. Lovari; M. Vitale; S. Romeo; U. Di Mario

Publisher
Springer
Year
2001
Tongue
English
Weight
74 KB
Volume
44
Category
Article
ISSN
0012-186X

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

The insulin sensitivity response is dete
The insulin sensitivity response is determined by the interaction between the G972R polymorphism of the insulin receptor substrate 1 gene and dietary fat
✍ Carmen MarΓ­n; Pablo PΓ©rez-MartΓ­nez; Javier Delgado-Lista; PurificaciΓ³n GΓ³mez; Fe πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 156 KB

## Abstract **Scope**: Insulin resistance, a condition associated with type 2 diabetes mellitus, results from the interaction of environmental and genetic factors. The aim of this study was to explore the influence of the G972R polymorphism at the insulin receptor substrate 1 gene on insulin sensit

Molecular scanning of the insulin recept
Molecular scanning of the insulin receptor substrate-1 (IRS-1) gene in Japanese patients with NIDDM: identification of five novel polymorphisms
✍ S. Ura; E. Araki; H. Kishikawa; T. Shirotani; M. Todaka; S. Isami; S. Shimoda; R πŸ“‚ Article πŸ“… 1996 πŸ› Springer 🌐 English βš– 989 KB

Since the insulin receptor substrate-1 (IRS-1) is the major substrate of the insulin receptor tyrosine kinase and has been shown to activate phosphatidylinositol (PI) 3-kinase and promote GLUT4 translocation, the IRS-1 gene is a potential candidate for development of non-insulin-dependent diabetes m