The G2019S LRRK2 mutation is uncommon amongst Greek patients with sporadic Parkinson's disease
β Scribed by K. Kalinderi; L. Fidani; S. Bostantjopoulou; Z. Katsarou; A. Kotsis
- Book ID
- 111065217
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 69 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1351-5101
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## Abstract Among mutations associated with autosomal dominant and sporadic Parkinson's disease (PD) the G2019S substitution in the leucineβrich repeat kinase 2 (LRRK2) gene is the most frequently identified. To estimate its frequency in Russia, we analyzed 208 patients with PD from the Northwester
## Abstract Mutations in the leucineβrich repeat kinase 2 (__LRRK2__) gene have been shown to cause autosomal dominant and sporadic Parkinson's disease (PD). We report here the frequency of a common heterozygous mutation, 2877510G>A, which produces a glycineβtoβserine amino acid substitution at cod
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