𝔖 Bobbio Scriptorium
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The functional significance of multimerization in ion channels

✍ Scribed by M Louise Tierney; Michael HB Stowell


Book ID
117656295
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
343 KB
Volume
8
Category
Article
ISSN
0959-440X

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## Abstract __MCOLN1__ encodes mucolipin‐1 (TRPML1), a member of the transient receptor potential TRPML subfamily of channel proteins. Mutations in __MCOLN1__ cause mucolipidosis‐type IV (MLIV), a lysosomal storage disorder characterized by severe neurologic, ophthalmologic, and gastrointestinal ab