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Mechanism and functional significance of TRPC channel multimerization

✍ Scribed by Mitchel L. Villereal

Book ID
116881252
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
176 KB
Volume
17
Category
Article
ISSN
1084-9521

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## Abstract __MCOLN1__ encodes mucolipin‐1 (TRPML1), a member of the transient receptor potential TRPML subfamily of channel proteins. Mutations in __MCOLN1__ cause mucolipidosis‐type IV (MLIV), a lysosomal storage disorder characterized by severe neurologic, ophthalmologic, and gastrointestinal ab