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The Frequency of Immortalization of Human Fibroblasts and Mammary Epithelial Cells Transfected with SV40 Large T-Antigen

โœ Scribed by Jerry W. Shay; Brigitte A. van der Haegen; Yan Ying; Woodring E. Wright


Book ID
115601582
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
493 KB
Volume
209
Category
Article
ISSN
0014-4827

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## BACKGROUND. The available human prostate cancer cell lines that are metastatic in athymic nude mice all have complex, highly aneuploid karyotypes. Other prostatic cells immortalized by transforming genes of SV40 or HPV and converted to tumorigenicity by additional genetic manipulation are not r