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The formation of intracellular glyceraldehyde-derived advanced glycation end-products and cytotoxicity

✍ Scribed by Jun-ichi Takino; Yuka Kobayashi; Masayoshi Takeuchi


Publisher
Springer Japan
Year
2010
Tongue
English
Weight
436 KB
Volume
45
Category
Article
ISSN
0944-1174

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## Abstract Cross‐linking of α‐synuclein and Lewy body formation have been implicated in the dopaminergic neuronal cell death observed in Parkinson's disease (PD); the mechanisms responsible, however, are not clear. Reactive oxygen species and advanced glycation end products (AGEs) have been found