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The Formal [3+2+1] Cyclisation of Cyclopropylamines with Carboxylic Anhydrides: A Quick Access to Polysubstituted 2,3,3a,4-Tetrahydro6(5H)-indolone Ring Systems

✍ Scribed by Laurent Larquetoux; Justyna A. Kowalska; Yvan Six


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
202 KB
Volume
2004
Category
Article
ISSN
1434-193X

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✍ Ouro Adetchessi; Daniel Desor; Isabelle Forfar; Christian Jarry; Jean Michel Leg 📂 Article 📅 1997 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 504 KB

## Abstract The reaction of 2‐amino‐2‐oxazolines with ethoxycarbonyl isocyanate was investigated in order to access to fused 1,3,5‐triazine‐2,4‐diones with a potential 5‐HT~2~ antagonist activity. The reaction leads to 2,3,6,7‐tetrahydro‐4__H__‐oxazolo[3,2‐__a__]‐1,3,5‐triazine‐2,4‐diones and to 1‐