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The folding and design of repeat proteins: reaching a consensus

✍ Scribed by Ewan RG Main; Sophie E Jackson; Lynne Regan


Book ID
114314645
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
404 KB
Volume
13
Category
Article
ISSN
0959-440X

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πŸ“œ SIMILAR VOLUMES


Consensus Design of Repeat Proteins
✍ Patrik Forrer; H. Kaspar Binz; Michael T. Stumpp; Andreas PlΓΌckthun πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 192 KB
Cover Picture: Consensus Design of Repea
✍ Patrik Forrer; H. Kaspar Binz; Michael T. Stumpp; Andreas PlΓΌckthun πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 19 KB

**The cover picture shows** an illustration of consensus design, a powerful protein‐engineering method that is based on sequence alignments of homologous proteins. An alignment of ankyrin repeats is shown in the sequence plane, and a consensus‐designed ankyrin repeat protein based on this alignment

Calorimetric study of a series of design
✍ Aitziber L. Cortajarena; Lynne Regan πŸ“‚ Article πŸ“… 2011 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 273 KB

## Abstract Repeat proteins comprise tandem arrays of a small structural motif. Their structure is defined and stabilized by interactions between residues that are close in the primary sequence. Several studies have investigated whether their structural modularity translates into modular thermodyna